Results

In a randomized clinical trial of forty people. Twenty used Tartarase for four weeks. Twenty were in the control group. Tartar was measured on the tongue side of the six lower front teeth — where it builds fastest and is hardest to reach.

In the Tartarase groups tartar fell by about 40%. In the control group, using an ordinary fluoride toothpaste, it rose by 12%.

Figure 1 from Milleman KR, Deener G, Milleman JL, Mish B, Schuller R, Mynarcik D. BMC Oral Health. 2024;24:720. doi.org/10.1186/s12903-024-04498-x — reproduced under CC BY 4.0. 

How to read this: each line is one person, from the start of the study to week four. Lower means less tartar.

In both Tartarase groups every line falls. In the control group almost every line rises.

Forty participants were randomly assigned to three groups: twenty used an ordinary fluoride toothpaste, ten brushed with Tartarase twice per day, and ten brushed with Tartarase and also wore a custom tray containing it for thirty minutes once daily. Tartar was scored at eighteen points per person using the Volpe-Manhold index, a standard clinical measure of deposit height.

This was a small proof-of-principle study — forty people over four weeks — and a larger, longer one is the natural next step. Eight adverse events were reported, all mild, all resolved within five days; one of them occurred in the control group.